ATCC® Number:VR-334™
Classification: Retrovirus, Avian Type C Retrovirus Group
Agent: Rous sarcoma virus
Strain: RAV-1 [Derived from Bryan high titer strain]
Original Source: chicken
Depositors: W Okazaki, HG Purchase
Biosafety Level:2
Shipped: frozen
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Host Organism : chicken embryo cells Avian species
Incubation : Duration: 4 days
Effect : Yes, in vitro effects: Transformation of cells
Comments : Antigenically identical to RAV-1, cross-reacts with antibodies to other avian leukosis viruses, transforming particle defective. Stable at -60C but not at -20C. This strain is a mixture of a defective transforming virus (Bryan RSV) and a replication competent helper virus, RAV-1.
References : 33497: Rubin H, Vogt PK. An avian leukosis virus associated with stocks of Rous sarcoma virus. Virology 17: 184-194, 1962. PubMed: 14494905 33498: Hanafusa H, et al. Analysis of the defectiveness of Rous sarcoma virus. I. Characterization of the helper virus. Virology 22: 591-601, 1964. PubMed: 14166120