ATCC® Number:VR-165™
Classification: Picornaviridae, Enterovirus, Human enterovirus A
Agent: Human Coxsackievirus A 6 deposited as Coxsackievirus A6
Strain: Gdula
Original Source: Stool from 5-year-old child with sore throat, fever and leg muscle spasm, New York, 1949
Depositors: HA Wenner
Biosafety Level:2
Shipped: frozen
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Host Organism : suckling mouse, s.c. inoculation or i.p. inoculation
Incubation : Duration: 2-3 days
Effect : Yes, in vivo effects: Flaccid paralysis
Comments : Paralysis develops in mice under 48 hours of age after i.p. inoculation of 10% suspension. Produces degeneration of muscle fibers including loss of striation and hyaline changes.
References : 32510: Dalldorf G. The coxsackie virus group. Ann. N.Y. Acad. Sci. 56: 583-586, 1953. PubMed: 13139263