ATCC® Number:VR-908™
Classification: Retrovirus, Avian Type C Retrovirus Group
Agent: Fujinami sarcoma
Strain: Fujinami
Original Source: chicken tumor
Depositors: H Hanafusa
Biosafety Level:2
Shipped: frozen
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Host Organism : chicken; duck; chicken embryo fibroblasts
Incubation : Duration: 3-5 days
Effect : Yes, tumorigenicity: Sarcomas in chickens and ducks Yes, in vitro effects: cell transformation in chicken embryo fibroblasts
Comments : Defective in replication and associated with Fujinami-associated virus, and avian leukosis virus as helper. The virus has biological features that distinguish it from the isolate of Peyton Rous.
References : 34006: Fujinami A, Inamoto K. . Z. Krebsforsch 14: 94, 1914. 34008: Gye WE. Br. J. Exp. Pathol. 12: 93, 1931. 34009: Smida J, Smidova V. Different tumorigenicity of avian RNA sarcoma viruses for some mammalian species. Neoplasma 19: 397-404, 1972. PubMed: 4345210 34010: Hanafusa T, et al. Characterization of the transforming gene of Fujinami sarcoma virus. Proc. Natl. Acad. Sci. USA 77: 3009-3013, 1980. PubMed: 6248881