ATCC® Number:VR-193™
Classification: Picornaviridae, Enterovirus, Poliovirus
Agent: Human poliovirus 3 (attenuated) deposited as Poliovirus 3 (attenuated)
Strain: Fox [Wy 3]
Original Source: Isolated from an asymptomatic patient, Louisiana
Depositors: H Koprowski
Biosafety Level:2
Shipped: frozen
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Host Organism : monkey kidney; human diploid cells
Incubation : Duration: 2-3 days
Effect : Yes, in vitro effects: Cytopathic effects in tissue culture
Comments : [The BMBL notes that all laboratory personnel working directly with the agent must have documented polio vaccination or demonstrated serologic evidence of immunity to all three poliovirus types. (CDC/NIH Biosafety in Microbiological and Biomedical Laboratories, 4th ed, 1999 - stock no. 017-040-00547-4)]. Strain has been found to be highly attenuated for monkey and for man (Koprowski).
References : 33218: Koprowski H. Discussion by Hilary Koprowski of Properties of attenuated polioviruses and their behavior in human beings by Albert B. Sabin. Spec. Publ. N.Y. Acad. Sci. 5: 128-133, 1957.